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1

Stereoselective pharmacokinetics of flobufen in rats

Frantisek Trejtnar, Vladimir Wsol, Barbora Szotakova, Lenka Skalova, Petr Pavek, Miroslav Kuchar

Journal:

Year:

1999

Language:

english

File:

PDF, 101 KB

english, 1999

2

Sex differences in stereospecificity of oracin reductases in rat in vitro and in vivo

Vladimír Wsól, Lenka Skálová, Barbora Szotáková, František Trejtnar, Eva Kvasničková

Journal:

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

3

Stereospecificity and stereoselectivity of flobufen metabolic profile in male rats in vitro and in vivo: Phase I of biotransformation

Vladimír Wsól, Radim Král, Lenka Skálová, Barbora Szotáková, František Trejtnar, Miroslav Flieger

Journal:

Year:

2001

Language:

english

File:

PDF, 236 KB

english, 2001

4

Stereoselective pharmacokinetics and metabolism of flobufen in guinea pigs

František Trejtnar, Radim Král, Petr Pávek, Vladimír Wsól

Journal:

Year:

2003

Language:

english

File:

PDF, 105 KB

english, 2003

5

Study of the biotransformation of a potential benzo[c]fluorene antineoplastic using high-performance liquid chromatography with high-speed-scanning ultraviolet detection

Milan Nobilis, Pavel Anzenbacher, Jiří Pastera, Zbyněk Svoboda, Kamil Hrubý, Jaroslav Květina, Karel Ubik, František Trejtnar

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1996

Language:

english

File:

PDF, 597 KB

english, 1996

6

Cytotoxicity decreasing effect and antimycobacterial activity of chitosan conjugated with antituberculotic drugs

Eva Vavříková, Jana Mandíková, František Trejtnar, Kata Horváti, Szilvia Bösze, Jiřina Stolaříková, Jarmila Vinšová

Journal:

Carbohydrate Polymers

Year:

2011

Language:

english

File:

PDF, 405 KB

english, 2011

7

In vitro comparison of renal handling and uptake of two somatostatin receptor-specific peptides labeled with indium-111

Frantisek Trejtnar, Zbynek Novy, Milos Petrik, Alice Laznickova, Ludmila Melicharova, Marie Vankova, Milan Laznicek

Journal:

Annals of Nuclear Medicine

Year:

2008

Language:

english

File:

PDF, 294 KB

english, 2008

8

Antimicrobial activity of sulfonamides containing 5-chloro-2-hydroxybenzaldehyde and 5-chloro-2-hydroxybenzoic acid scaffold

Martin Krátký, Jarmila Vinšová, Marie Volková, Vladimír Buchta, František Trejtnar, Jiřina Stolaříková

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 343 KB

english, 2012

9

Metabolic pathways of flobufen — a new antirheumatic and antiarthritic drug. Interspecies comparison

Eva Kvasnicková, Barbora Szotáková, Vladimír Wsól, František Trejtnar, Lenka Skálová, Ivo M. Hais, Miroslav Kuchar, Marie Poppová

Journal:

Experimental and Toxicologic Pathology

Year:

1999

Language:

english

File:

PDF, 771 KB

english, 1999

10

Possible use of excretion of tubular epithelial cells for the study of the nephrotoxic effect of xenobiotics

Věra Štětinová, František Trejtnar, Jiří Kopecký, Vojtěch Grossmann, Jaroslav Květina, Libuše Kopecká, Vladimír Semecký

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

1996

Language:

english

File:

PDF, 1.53 MB

english, 1996

11

Iron reduction potentiates hydroxyl radical formation only in flavonols

Kateřina Macáková, Přemysl Mladěnka, Tomáš Filipský, Michal Říha, Luděk Jahodář, František Trejtnar, Paolo Bovicelli, Ilaria Proietti Silvestri, Radomír Hrdina, Luciano Saso

Journal:

Year:

2012

Language:

english

File:

PDF, 886 KB

english, 2012

12

Analysis of accumulation of 99mTc-octreotide and 99mTc-EDDA/HYNIC-Tyr3-octreotide in the rat kidneys

Martin Kopecky, Vladimir Semecky, Frantisek Trejtnar, Milan Laznicek, Alice Laznickova, Petr Nachtigal, Clemens Decristoforo, Stephen J. Mather, Helmut R. Mäcke

Journal:

Nuclear Medicine and Biology

Year:

2004

Language:

english

File:

PDF, 406 KB

english, 2004

13

Comparison of 99mTc-mercaptoacetyltriglycine and [131I]-o-iodohippurate elimination in perfused rat kidney

Frantisek Trejtnar, Milan Laznicek, Alice Laznickova

Journal:

Nuclear Medicine and Biology

Year:

2003

Language:

english

File:

PDF, 88 KB

english, 2003

14

Synthesis and antimycobacterial evaluation of pyrazinamide derivatives with benzylamino substitution

Zitko, Jan, Paterová, Pavla, Kubíček, Vladimír, Mandíková, Jana, Trejtnar, František, Kuneš, Jiří, Doležal, Martin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 286 KB

english, 2013

15

Synthesis and in vitro antimycobacterial activity of 2-methoxybenzanilides and their thioxo analogues

Kozic, Ján, Novotná, Eva, Volková, Marie, Stolaříková, Jiřina, Trejtnar, František, Vinšová, Jarmila

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 376 KB

english, 2012

16

Synthesis and in vitro antimycobacterial and isocitrate lyase inhibition properties of novel 2-methoxy-2′-hydroxybenzanilides, their thioxo analogues and benzoxazoles

Kozic, Ján, Novotná, Eva, Volková, Marie, Stolaříková, Jiřina, Trejtnar, František, Wsól, Vladimír, Vinšová, Jarmila

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 498 KB

english, 2012

17

A comparison of in vitro methods for determining the membrane receptor expression in cell lines

Zbynek Novy, Pavel Barta, Jana Mandikova, Milan Laznicek, Frantisek Trejtnar

Journal:

Nuclear Medicine and Biology

Year:

2012

Language:

english

File:

PDF, 182 KB

english, 2012

18

Synthesis and in vitro evaluation of new derivatives of 2-substituted-6-fluorobenzo[d]thiazoles as cholinesterase inhibitors

Imramovský, Aleš, Pejchal, Vladimír, Štěpánková, Šárka, Vorčáková, Katarína, Jampílek, Josef, Vančo, Ján, Šimůnek, Petr, Královec, Karel, Brůčková, Lenka, Mandíková, Jana, Trejtnar, František

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 662 KB

english, 2013

19

Highly sensitive fast determination of entecavir in rat urine by means of hydrophilic interaction chromatography–ultra-high-performance liquid chromatography–tandem mass spectrometry

Nováková, Lucie, Gottvald, Tomáš, Vlčková, Hana, Trejtnar, František, Mandíková, Jana, Solich, Petr

Journal:

Journal of Chromatography A

Year:

2012

Language:

english

File:

PDF, 727 KB

english, 2012

20

Interactions with selected drug renal transporters and transporter-mediated cytotoxicity in antiviral agents from the group of acyclic nucleoside phosphonates

Mandíková, Jana, Volková, Marie, Pávek, Petr, Česnek, Michal, Janeba, Zlatko, Kubíček, Vladimír, Trejtnar, František

Journal:

Year:

2013

Language:

english

File:

PDF, 873 KB

english, 2013

21

Salicylanilide diethyl phosphates: Synthesis, antimicrobial activity and cytotoxicity

Vinšová, Jarmila, Kozic, Ján, Krátký, Martin, Stolaříková, Jiřina, Mandíková, Jana, Trejtnar, František, Buchta, Vladimír

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 558 KB

english, 2014

22

How to address the sample preparation of hydrophilic compounds: Determination of entecavir in plasma and plasma ultrafiltrate with novel extraction sorbents

Vlčková, Hana, Janák, Jaroslav, Gottvald, Tomáš, Trejtnar, František, Solich, Petr, Nováková, Lucie

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2014

Language:

english

File:

PDF, 903 KB

english, 2014

23

Synthesis and biological activity of new salicylanilide N,N-disubstituted carbamates and thiocarbamates

Krátký, Martin, Volková, Marie, Novotná, Eva, Trejtnar, František, Stolaříková, Jiřina, Vinšová, Jarmila

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 624 KB

english, 2014

24

Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase

Krátký, Martin, Vinšová, Jarmila, Novotná, Eva, Mandíková, Jana, Wsól, Vladimír, Trejtnar, František, Ulmann, Vít, Stolaříková, Jiřina, Fernandes, Steve, Bhat, Shridhar, Liu, Jun O.

Journal:

Year:

2012

Language:

english

File:

PDF, 255 KB

english, 2012

25

Determination of receptor protein binding site specificity and relative binding strength using a time-resolved competition assay

Barta, Pavel, Volkova, Marie, Dascalu, Adrian, Spiegelberg, Diana, Trejtnar, Frantisek, Andersson, Karl

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

26

Distribution, Elimination, and Renal Handling of 99m Technetium-Demogastrin 1

Trejtnar, Frantisek, Laznickova, Alice, Laznicek, Milan, Novy, Zbynek, Maina, Theodosia, Nock, Berthold A., Behe, Martin

Journal:

Cancer Biotherapy & Radiopharmaceuticals

Year:

2012

Language:

english

File:

PDF, 146 KB

english, 2012

27

The effect of chelator type on in vitro receptor binding and stability in 177 Lu-labeled cetuximab and panitumumab

Novy, Zbynek, Laznickova, Alice, Mandikova, Jana, Barta, Pavel, Laznicek, Milan, Trejtnar, Frantisek

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2014

Language:

english

File:

PDF, 507 KB

english, 2014

28

Synthesis and antimicrobial activity of sulphamethoxazole-based ureas and imidazolidine-2,4,5-triones

Krátký, Martin, Mandíková, Jana, Trejtnar, František, Buchta, Vladimír, Stolaříková, Jiřina, Vinšová, Jarmila

Journal:

Chemical Papers

Year:

2015

Language:

english

File:

PDF, 266 KB

english, 2015

29

Biotransformation of anthelmintics and the activity of drug-metabolizing enzymes in the tapeworm Moniezia expansa

PRCHAL, LUKÁŠ, BÁRTÍKOVÁ, HANA, BEČANOVÁ, ANETA, JIRÁSKO, ROBERT, VOKŘÁL, IVAN, STUCHLÍKOVÁ, LUCIE, SKÁLOVÁ, LENKA, KUBÍČEK, VLADIMÍR, LAMKA, JIŘÍ, TREJTNAR, FRANTIŠEK, SZOTÁKOVÁ, BARBORA

Journal:

Year:

2015

Language:

english

File:

PDF, 338 KB

english, 2015

30

Novel derivatives of nitro-substituted salicylic acids: Synthesis, antimicrobial activity and cytotoxicity

Paraskevopoulos, Georgios, Krátký, Martin, Mandíková, Jana, Trejtnar, František, Stolaříková, Jiřina, Pávek, Petr, Besra, Gurdyal, Vinšová, Jarmila

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 617 KB

english, 2015

31

Design, synthesis and anti-mycobacterial evaluation of some newN-phenylpyrazine-2-carboxamides

Zitko, Jan, Servusová-Vaňásková, Barbora, Paterová, Pavla, Navrátilová, Lucie, Trejtnar, František, Kuneš, Jiří, Doležal, Martin

Journal:

Chemical Papers

Year:

2016

Language:

english

File:

PDF, 323 KB

english, 2016

32

Cover Picture: Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis (ChemMedChem 8/2015)

Česnek, Michal, Jansa, Petr, Šmídková, Markéta, Mertlíková-Kaiserová, Helena, Dračínský, Martin, Brust, Tarsis F., Pávek, Petr, Trejtnar, František, Watts, Val J., Janeba, Zlatko

Journal:

Year:

2015

File:

PDF, 603 KB

2015

33

99mTc demotate 1: biodistribution and elimination characteristics in rats

Kopecky, Martin, Trejtnar, Frantisek, Laznicek, Milan, Laznickova, Alice, Semecky, Vladimir, Maina, Theodosia, Nock, Berthold

Journal:

Nuclear Medicine Communications

Year:

2005

Language:

english

File:

PDF, 136 KB

english, 2005

34

Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation

Hyrsova, Lucie, Smutny, Tomas, Trejtnar, Frantisek, Pavek, Petr

Journal:

Drug Metabolism Reviews

Year:

2016

Language:

english

File:

PDF, 1.83 MB

english, 2016

35

ChemInform Abstract: Synthesis and in vitro Antimycobacterial and Isocitrate Lyase Inhibition Properties of Novel 2-Methoxy-2′-hydroxybenzanilides, Their Thioxo Analogues and Benzoxazoles.

Kozic, Jan, Novotna, Eva, Volkova, Marie, Stolarikova, Jirina, Trejtnar, Frantisek, Wsol, Vladimir, Vinsova, Jarmila

Journal:

Year:

2013

File:

PDF, 30 KB

2013

36

The in vivo disposition and in vitro transmembrane transport of two model radiometabolites of DOTA-conjugated receptor-specific peptides labelled with 177 Lu

Volková, Marie, Mandíková, Jana, Bárta, Pavel, Navrátilová, Lucie, Lázníčková, Alice, Trejtnar, František

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2015

Language:

english

File:

PDF, 270 KB

english, 2015

37

The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for (“squelching”) SRC-1 coactivator

Hyrsova, Lucie, Smutny, Tomas, Carazo, Alejandro, Moravcik, Stefan, Mandikova, Jana, Trejtnar, Frantisek, Gerbal-Chaloin, Sabine, Pavek, Petr

Journal:

British Journal of Pharmacology

Year:

2016

Language:

english

File:

PDF, 611 KB

english, 2016

38

Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis

Česnek, Michal, Jansa, Petr, Šmídková, Markéta, Mertlíková-Kaiserová, Helena, Dračínský, Martin, Brust, Tarsis F., Pávek, Petr, Trejtnar, František, Watts, Val J., Janeba, Zlatko

Journal:

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

39

In vitro evaluation of concentration, labeling effectiveness and stability for 131 I-labeled radioimmunoassay ligand using real-time detection technology

Barta, Pavel, Janousek, Jiri, Zilkova, Katerina, Trejtnar, Frantisek

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2017

Language:

english

File:

PDF, 329 KB

english, 2017

40

Novel salicylanilides from 4,5-dihalogenated salicylic acids: Synthesis, antimicrobial activity and cytotoxicity

Paraskevopoulos, Georgios, Monteiro, Sara, Vosátka, Rudolf, Krátký, Martin, Navrátilová, Lucie, Trejtnar, František, Stolaříková, Jiřina, Vinšová, Jarmila

Journal:

Bioorganic & Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 835 KB

english, 2017

41

Synthesis of readily available fluorophenylalanine derivatives and investigation of their biological activity

Krátký, Martin, Štěpánková, Šárka, Vorčáková, Katarína, Navrátilová, Lucie, Trejtnar, František, Stolaříková, Jiřina, Vinšová, Jarmila

Journal:

Bioorganic Chemistry

Year:

2017

Language:

english

File:

PDF, 843 KB

english, 2017

42

Corrigendum to “Novel salicylanilides from 4,5-dihalogenated salicylic acids: Synthesis, antimicrobial activity and cytotoxicity” [Bioorg. Med. Chem. 25 (2017) 1524–1532]

Paraskevopoulos, Georgios, Monteiro, Sara, Vosátka, Rudolf, Krátký, Martin, Navrátilová, Lucie, Trejtnar, František, Stolaříková, Jiřina, Vinšová, Jarmila

Journal:

Bioorganic & Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 158 KB

english, 2017

43

Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl hydrocarbon (AHR) receptors in detoxification regulation

Dusek, Jan, Carazo, Alejandro, Trejtnar, Frantisek, Hyrsova, Lucie, Holas, Ondřej, Smutny, Tomas, Micuda, Stanislav, Pavek, Petr

Journal:

Food and Chemical Toxicology

Year:

2017

Language:

english

File:

PDF, 2.99 MB

english, 2017

44

New lipophilic isoniazid derivatives and their 1,3,4-oxadiazole analogues: Synthesis, antimycobacterial activity and investigation of their mechanism of action

Vosátka, Rudolf, Krátký, Martin, Švarcová, Markéta, Janoušek, Jiří, Stolaříková, Jiřina, Madacki, Jan, Huszár, Stanislav, Mikušová, Katarína, Korduláková, Jana, Trejtnar, František, Vinšová, Jarmila

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 918 KB

english, 2018

45

Interaction of soy isoflavones and their main metabolites with hOATP2B1 transporter

Navrátilová, Lucie, Applová, Lenka, Horký, Pavel, Mladěnka, Přemysl, Pávek, Petr, Trejtnar, František

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

46

Antibacterial Activity of Salicylanilide 4-(Trifluoromethyl)-benzoates

Krátký, Martin, Vinšová, Jarmila, Novotná, Eva, Mandíková, Jana, Trejtnar, František, Stolaříková, Jiřina

Journal:

Year:

2013

Language:

english

File:

PDF, 281 KB

english, 2013

47

Sulfadiazine Salicylaldehyde-Based Schiff Bases: Synthesis, Antimicrobial Activity and Cytotoxicity

Krátký, Martin, Dzurková, Magdaléna, Janoušek, Jiří, Konečná, Klára, Trejtnar, František, Stolaříková, Jiřina, Vinšová, Jarmila

Journal:

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

48

Entecavir Interacts with Influx Transporters hOAT1, hCNT2, hCNT3, but Not with hOCT2: The Potential for Renal Transporter-Mediated Cytotoxicity and Drug–Drug Interactions

Mandíková, Jana, Volková, Marie, Pávek, Petr, Navrátilová, Lucie, Hyršová, Lucie, Janeba, Zlatko, Pavlík, Jan, Bárta, Pavel, Trejtnar, František

Journal:

Frontiers in Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.38 MB

english, 2016

49

Correction to: Interaction of soy isoflavones and their main metabolites with hOATP2B1 transporter

Navrátilová, Lucie, Applová, Lenka, Horký, Pavel, Mladěnka, Přemysl, Pávek, Petr, Trejtnar, František

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2018

Language:

english

File:

PDF, 284 KB

english, 2018

50

3-Substituted N-Benzylpyrazine-2-carboxamide Derivatives: Synthesis, Antimycobacterial and Antibacterial Evaluation

Semelková, Lucia, Janďourek, Ondřej, Konečná, Klára, Paterová, Pavla, Navrátilová, Lucie, Trejtnar, František, Kubíček, Vladimír, Kuneš, Jiří, Doležal, Martin, Zitko, Jan

Journal:

Year:

2017

Language:

english

File:

PDF, 1.06 MB

english, 2017